2013-2014全美药品处方量和销售额榜单Top100

2013-2014全美药品处方量和销售额榜单Top100 发布日期：2014-05-14  来源：IMS Health  
近日全美药品Top100榜单推出，在2013年4月至2014年3月这跌宕起伏的一年中，各大药商你来我往，且看谁主沉浮。

                               
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其中，甲状腺机能减退症药物，左旋甲状腺素（Synthroid，艾伯维），月处方量继续占据全美处方量榜首；抗精神病药阿立哌唑（Abilify，大冢制药）则领衔全美药品销量榜，据艾美仕研究公司（ IMS Health）的最新统计，该药目前销售额达到惊人的69亿美元。
这些数据清晰地反映了在2013年4月至2014年3月这跌宕起伏的一年中，全美药品总销量和总处方量的沉浮更替。
可以看出，左旋甲状腺素以2300万领跑处方榜，而紧随其后的是降胆固醇药物瑞舒伐他汀（Crestor，阿斯利康），该药处方量也达到惊人的2290万；质子泵抑制剂埃索美拉唑（耐信，阿斯利康）则以1930万屈居第三。哮喘药物沙丁胺醇（ventolin HFA，葛兰素史克）保持在1750万；慢性阻塞性肺病治疗药物氟替卡松/沙美特罗（Advair Diskus，葛兰素史克）也有不错的表现，其处方量超过了1550万。
榜单前十名之后，抗抑郁药度洛西汀（Cymbalta，礼来制药）、抗高血压药缬沙坦分散片（Diovan，诺华公司）、注意力缺失症药物二甲磺酸赖右苯丙胺（Vyvanse，希雷公司）、甘精胰岛素（Lantus Solostar，赛诺菲）、以及癫痫药物普瑞巴林（Lyrica，辉瑞制药），分列次席。
另一方面，销量榜单上紧咬阿立哌唑（Abilify，大冢制药）的是销量保持63亿美元的埃索美拉唑（耐信，阿斯利康）以及销量达59亿美元的抗关节炎药物阿达木单抗（Humira，艾伯维）。
紧随榜单Top10的畅销药还包括瑞舒伐他汀（Crestor，55亿），Advair Diskus（51亿），哮喘药物依那西普（Enbrel，美国安进；约49亿）以及英夫利昔（Remicade，山陶克；42亿）、Cymbalta（41亿）、多发性硬化症药物醋酸格拉替雷（Copaxone，Teva Pharm；接近37亿）、嗜中性白血球减少症药物乙二醇化非格司亭（Neulasta，美国安进；36亿美元）。

Table 1. Top 100 Drugs by Sales
Rank	Drug (Brand Name)	Sales Through March 2014
1	Abilify	$6,885,243,368
2	Nexium	$6,271,376,299
3	Humira	$5,936,288,498
4	Crestor	$5,502,148,010
5	Advair Diskus	$5,112,576,549
6	Enbrel	$4,896,267,318
7	Remicade	$4,235,535,358
8	Cymbalta	$4,095,537,942
9	Copaxone	$3,679,837,035
10	Neulasta	$3,634,919,067
11	Lantus Solostar	$3,375,632,862
12	Rituxan	$3,320,475,967
13	Spiriva Handihaler	$3,140,602,715
14	Januvia	$2,975,320,499
15	Atripla	$2,894,627,347
16	Lantus	$2,796,784,267
17	Avastin	$2,742,284,655
18	Lyrica	$2,611,451,728
19	Oxycontin	$2,528,601,587
20	Epogen	$2,346,224,521
21	Celebrex	$2,342,549,444
22	Truvada	$2,307,970,304
23	Diovan	$2,190,542,692
24	Gleevec	$1,995,042,989
25	Herceptin	$1,971,724,243
26	Lucentis	$1,917,919,037
27	Namenda	$1,871,956,353
28	Vyvanse	$1,848,814,801
29	Zetia	$1,826,260,072
30	Levemir	$1,775,037,064
31	Symbicort	$1,733,830,589
32	Sovaldi	$1,724,867,241
33	Novolog Flexpen	$1,482,659,229
34	Novolog	$1,409,680,368
35	Tecfidera	$1,394,704,148
36	Suboxone	$1,388,805,102
37	Humalog	$1,310,236,982
38	Xarelto	$1,263,697,546
39	Seroquel XR	$1,251,615,894
40	Viagra	$1,235,125,299
41	Alimta	$1,205,717,422
42	Victoza 3-Pak	$1,186,784,355
43	Avonex	$1,184,476,004
44	Nasonex	$1,180,165,756
45	Cialis	$1,170,843,904
46	Gilenya	$1,097,409,827
47	Stelara	$1,083,660,282
48	Flovent HFA	$1,078,422,967
49	Prezista	$1,046,464,870
50	Procrit	$1,037,298,436
51	Isentress	$1,037,220,122
52	Janumet	$1,028,179,032
53	Renvela	$1,023,751,529
54	Humalog Kwikpen	$1,003,100,788
55	Orencia	$990,449,529
56	Dexilant	$967,408,551
57	Vesicare	$967,408,277
58	Neupogen	$944,389,150
59	Reyataz	$935,417,307
60	Lunesta	$927,689,337
61	Synthroid	$899,215,664
62	Pradaxa	$862,604,444
63	Zytiga	$861,683,197
64	Benicar	$860,761,655
65	Xolair	$859,052,353
66	Avonex Pen	$849,256,894
67	Vytorin	$846,602,646
68	Invega Sustenna	$831,061,694
69	Sensipar	$824,871,721
70	Xgeva	$822,603,435
71	Prevnar 13	$821,372,081
72	Evista	$815,315,970
73	Aranesp	$814,017,366
74	Betaseron	$792,093,855
75	Stribild	$785,645,319
76	Combivent Respimat	$768,925,543
77	Xeloda	$761,832,629
78	Afinitor	$761,796,538
79	Ventolin HFA	$761,324,992
80	Synagis	$755,220,544
81	Zyvox	$732,206,096
82	Bystolic	$719,917,435
83	Sandostatin LAR	$708,264,105
84	Complera	$696,270,123
85	Benicar HCT	$692,128,910
86	Treanda	$691,670,874
87	Gardasil	$683,558,728
88	Zostavax	$679,653,129
89	Pristiq	$660,397,547
90	Erbitux	$660,368,777
91	Focalin XR	$647,720,027
92	Tarceva	$646,108,218
93	Cubicin	$643,649,546
94	Strattera	$640,562,124
95	Latuda	$639,903,393
96	Velcade	$624,619,639
97	Viread	$606,046,798
98	Welchol	$603,644,260
99	Nuvaring	$600,191,343
100	Sprycel	$599,882,414
Source: IMS National Prescription Audit, IMS Health.

Table 2. Top 100 Drugs by Monthly Prescription
Rank	Drug (Brand Name)	Total Prescriptions
1	Synthroid	23,025,870
2	Crestor	22,868,588
3	Nexium	19,327,244
4	Ventolin HFA	17,503,208
5	Advair Diskus	15,545,755
6	Cymbalta	14,487,742
7	Diovan	12,017,281
8	Vyvanse	9,914,366
9	Lantus Solostar	9,858,068
10	Lyrica	9,578,165
11	Spiriva Handihaler	9,498,944
12	Lantus	9,465,389
13	Celebrex	8,961,654
14	Januvia	8,753,604
15	Abilify	8,747,749
16	Namenda	8,290,471
17	Viagra	7,700,014
18	Zetia	7,558,029
19	Cialis	7,538,599
20	Nasonex	7,535,817
21	Suboxone	7,014,057
22	Bystolic	6,774,283
23	Symbicort	6,481,953
24	Flovent HFA	5,682,958
25	Oxycontin	5,604,176
26	Levemir	5,303,924
27	Nuvaring	5,025,087
28	Dexilant	4,963,772
29	Benicar	4,812,577
30	Thyroid	4,652,869
31	Voltaren Gel	4,522,268
32	Proventil HFA	4,463,319
33	Xarelto	4,298,882
34	Premarin	4,192,083
35	Novolog	4,110,590
36	Tamiflu	3,980,340
37	Novolog Flexpen	3,972,636
38	Vesicare	3,952,080
39	Benicar HCT	3,731,887
40	Humalog	3,726,949
41	Afluria	3,245,099
42	Lumigan	3,243,154
43	Vytorin	3,220,389
44	Toprol-XL	3,183,372
45	Lunesta	3,156,599
46	Janumet	3,143,830
47	Ortho-Tri-Cy Lo 28	3,121,888
48	Pristiq	3,119,322
49	Lo Loestrin Fe	3,055,273
50	Focalin XR	3,036,103
51	Travatan Z	2,967,478
52	Evista	2,843,095
53	Pataday	2,716,789
54	Combivent Respimat	2,611,915
55	Avodart	2,610,028
56	Pradaxa	2,512,418
57	Humalog Kwikpen	2,467,999
58	Seroquel XR	2,423,659
59	Strattera	2,396,488
60	Zostavax	2,207,535
61	Chantix	2,149,709
62	Exforge	1,896,838
63	Exelon	1,892,680
64	Humira	1,882,887
65	Loestrin 24 Fe	1,860,833
66	Victoza 3-Pak	1,852,187
67	Welchol	1,808,313
68	Combigan	1,798,617
69	Onglyza	1,796,175
70	Xopenex HFA	1,792,808
71	Detrol La	1,734,896
72	Premarin Vaginal	1,701,245
73	Minastrin 24 Fe	1,699,982
74	Enbrel	1,621,584
75	Dulera	1,608,644
76	Ranexa	1,530,049
77	Truvada	1,523,457
78	Alphagan P	1,510,617
79	Actonel	1,480,998
80	Azor	1,463,567
81	Effient	1,438,820
82	Viibryd	1,428,488
83	Levitra	1,404,878
84	Norvir	1,387,510
85	Lipitor	1,381,007
86	Tradjenta	1,358,963
87	Aggrenox	1,349,620
88	Patanol	1,341,851
89	Amitiza	1,296,453
90	Advair Hfa	1,277,594
91	Lotemax	1,269,637
92	Uloric	1,228,713
93	Ortho Evra 3	1,213,526
94	Asmanex Twisthaler	1,212,978
95	Prempro Low Dose	1,208,140
96	Micardis	1,200,868
97	Atripla	1,197,347
98	Novolog Flxpen Mix 70/30	1,134,749
99	Aciphex	1,114,495
100	Humulin N	1,092,969
Source: IMS National Prescription Audit, IMS Health.